Table 1. Clinical characteristics of patients according to NYHA class.
|
Clinical variables |
I NYHA |
II NYHA |
III NYHA |
IV NYHA |
p value |
|
( n=32) |
(n=78) |
(n=62) |
(n=31) |
||
|
Age, years (mean±SD) |
48.25±10.12‡ |
53.95.0±13.53 |
57.47±12.07 |
61.09±16.40” |
0.007 |
|
Male (n, %) |
26 (80) |
67 (85.7) ǂ |
50 (80.3) |
19 (61.3) |
0.043* |
|
Female (n, %) |
6 (20) ’ |
11 (14.3) |
12 (19.7) |
12 (38.7) |
0.060* |
|
Left ventricular ejection fraction (%,mean±SD) |
34.28±11.45‡ |
29.09±11.06 |
28.88±12.40 |
26.65±11.65” |
0.045 |
|
6 min walking test, (mean±SD) |
526.09±99.89‡ |
471.23±82.96 ǂ |
378.9±127.10+ |
273.18±143.18” |
0.002 |
|
BMI (median, min-max) |
28.68(19-37) |
27.38(19-43) |
26.54(21-44) |
25.10(20-45)” |
0.005 |
|
SBP (mean±SD) |
137.38±18.97‡’ |
124.81±17.84 |
125.26±20.76 |
118.42±23.63” |
0.035 |
|
DBP (mean±SD) |
85.75±10.97 |
82.12±12.45 |
80.73±13.79 |
76.23±11.61” |
0.008 |
Note. BMI-body mass index, SBP-systolic blood pressure, DBP-diastolic blood pressure, ǂ - statistically significant difference between NYHA II and NYHA IV, +- statistically significant difference between NYHA II and NYHA III, ‡ - statistically significant difference between NYHA I and NYHA III patients, "- statistically significant difference between NYHA I and NYHA IV patients, ‘-statistically significant difference between NYHA I and NYHA II patients. *- the comparisons were made using the chi-square test; the Welch’s test was used for other variables.