Table 1. Prediction of the presence of the signal peptide (SP) in chimeric renalases.
|
Protein |
Phobius |
TargetP-2.0 |
SignalP-5.0 |
SecretomeP 2.0a |
|
RNLS |
Non cytoplasmic |
Mitochondrial |
SP- |
0,622; SP+ |
|
RNLS without N-terminus |
Non cytoplasmic |
SP- |
SP- |
0.645; SP- |
|
Albumin |
Non cytoplasmic |
SP- |
SP- |
0.556; SP- |
|
Prolactin |
Non cytoplasmic |
SP+ |
SP+ |
0.799; SP+ |
|
ACE |
Non cytoplasmic |
SP+ |
SP+ |
0.879; SP+ |
|
Integrin |
Non cytoplasmic |
SP+ |
SP+ |
0.738; SP+ |
|
Serpin |
Non cytoplasmic |
SP+ |
SP+ |
0.652; SP+ |
|
Thrombin |
Non cytoplasmic |
SP+ |
SP+ |
0.745; SP+ |
Note. In SecretomeP 2.0a (predicts non-classical secretory proteins), secreted proteins should have a score of >0.6 and no signal peptide)